Historical routes[ edit ] According to most sources, French chemist Charles-Adolphe Wurtz — first prepared ethylene glycol in Wurtz named his new compound "glycol" because it shared qualities with both ethyl alcohol with one hydroxyl group and glycerin with three hydroxyl groups. In the United States, semicommercial production of ethylene glycol via ethylene chlorohydrin started in By , ethylene glycol was being used by almost all dynamite manufacturers.
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ReAgent supply ethanediol for laboratory use in 2. This product is sold with minimum levels of impurities, including 0. Further information can be downloaded from our Sales Product Specification available online.
Ethanediol Poisoning This compound is a highly toxic product if ingested. Due to its sweet taste, there are many reports of accidental ingestion particularly of antifreeze products, by children and pets. Intoxication symptoms can be divided in 3 stages: Stage 1 — up to 12 hours after ingestion: Dizziness, incoordination of muscle movements, headaches and confusion, followed by nausea and vomiting Stage 2 — 12 to 36 hours after ingestion: Increased heart rate, high blood pressure and metabolic acidosis as a result of the accumulation of glycolic and oxalic acids in the bloodstream.
If not treated in time, this could be fatal. Stage 3 — 24 to 72 hours after ingestion: high levels of potassium in the blood, acute tubular necrosis, blood in the urine, lower back pain and acute kidney failure.
The most accurate way of diagnosis is by assessing the level of ethanediol directly in the blood. If doctors do not have the facilities to perform this test, diagnosis can be done by the presence of oxalate crystals in the urine.
Treatment involves the use of antidotes, such as ethanol or fomepizole, which block the enzyme capable of metabolising ethanediol. If treatment is initiated in time, most patients can make a full recovery. We have a wide range of products, from pharmaceuticals and test kits to speciality and bespoke solutions, supported by a friendly customer service team willing to help.
Simply contact us for further information and free technical advice.
Ethanediol (Laboratory Use)